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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COBRA1
All Species:
28.79
Human Site:
Y541
Identified Species:
63.33
UniProt:
Q8WX92
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WX92
NP_056271.2
580
65697
Y541
G
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
Chimpanzee
Pan troglodytes
XP_001136264
336
37293
S298
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
E
Rhesus Macaque
Macaca mulatta
XP_001087434
579
64739
Y540
G
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
Dog
Lupus familis
XP_548351
580
65729
Y541
G
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4Y3
580
65618
Y541
G
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
Rat
Rattus norvegicus
NP_001101287
580
65616
Y541
G
E
A
V
K
E
L
Y
S
Q
L
G
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006202
577
65823
K538
K
Q
S
G
E
A
V
K
E
L
H
N
Q
L
T
Frog
Xenopus laevis
NP_001089871
577
65679
K538
K
T
S
G
E
P
L
K
E
L
Y
N
T
L
S
Zebra Danio
Brachydanio rerio
NP_956462
583
66419
Y540
S
E
S
V
K
E
L
Y
N
L
L
K
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y113
594
67916
Y553
N
E
H
I
H
K
L
Y
E
I
L
Q
E
R
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781074
640
72782
Y536
S
Q
A
V
R
D
L
Y
S
S
V
M
E
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
88.6
96.2
N.A.
95.8
96.5
N.A.
N.A.
86.7
78.9
75.4
N.A.
51.5
N.A.
N.A.
50.6
Protein Similarity:
100
46.7
91
98.2
N.A.
98
98.6
N.A.
N.A.
94.6
88
86.9
N.A.
68.8
N.A.
N.A.
66
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
66.6
N.A.
33.3
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
33.3
20
80
N.A.
60
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
55
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
64
0
0
28
55
0
0
28
0
0
10
73
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
46
0
0
19
0
0
0
0
0
0
10
46
0
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
19
% I
% Lys:
19
0
0
10
55
10
0
19
0
0
0
10
10
64
0
% K
% Leu:
0
0
0
0
0
10
82
0
0
37
64
0
0
28
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
19
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
0
0
0
0
0
10
46
0
10
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
19
0
28
0
0
0
0
10
55
10
0
0
0
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% T
% Val:
0
0
10
64
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
73
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _